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Non-Adherence to the Guideline Recommended Pharmacologic Therapy in Patients with Reduced Left Ventricle (LV) Ejection Fraction (HFrEF)

. Dr. Ateeb Mahmood Khan, Aijaz Ali Kaleri, Dr. Nehrish Patel, Naeem Ullah Khan, Dr Faizan Abdul Aziz Wallam, Tahir Hussain & Dr. Asadullah Kundi


Abstract

The aim of the present study was to ascertain how closely heart failure patients with reduced ejection fraction (HFrEF) adhere to the pharmaceutical therapy that is advised by guidelines. Total 137 patients were taken for the proposed research study. According to the Morisky medication adherence score, 36.5% of the participants in our study were found to have insufficient adherence. Age (elderly), cognitive impairment, the use of multiple medications and monthly income were significant contributors to non-adherence. Every piece of data was acquired using a pre-made proforma. Patients were asked questions on their drug adherence using the eight-question Morisky tool. Following that, it was divided into two categories: appropriate adherence (score 6 or above) and insufficient compliance (score 5 or below). In patients with heart failure, satisfactory adherence to the pharmaceutical therapy prescribed by guidelines was noted in 63.5 percent of cases. 63.5 percent of participants in this study were found to have good adherence to their prescription regimens (Morisky score of 6 or above). Nonetheless, it was noted that 36.5 percent of the HFrEF patients in our study had inadequate adherence. Increasing drug adherence requires regular patient counselling and the care they receive.

 

Keywords: pharmaceutical therapy adherence by guidelines, heart failure, and drug adherence.

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