Numerous nonsteroidal anti-inflammatory drugs have been shown to alleviate pain and inflammation by inhibiting the cyclooxygenase enzyme isoform, thereby reducing the synthesis of prostaglandins from arachidonic acid. Unfortunately, the use of these drugs is associated with a range of adverse effects. However, there exists a group of medicinal plants that exhibit anti- inflammatory therapeutic properties with minimal or no adverse effects. These plants have proven successful in treating inflammatory disorders in conventional medicine. It's noteworthy that researchers have extensively studied and documented the biological and therapeutic effects of some common medicinal plants. Regrettably, there is a notable absence of a comprehensive review paper cataloging medicinal plants with anti-inflammatory properties across various African nations. Recognizing the significance of ethnobotanical knowledge, it is crucial to document and understand the applications of anti-inflammatory medicinal plants from selected countries representing different regions of the African continent. This approach aims to illustrate the diverse array of medicinal plants utilized for traditional or therapeutic purposes globally, and the present study enumerates the anti-inflammatory properties of several such plants from varied geographic regions

Keywords: Inflammation, Anti-inflammatory conditions, local plants, plant potentials.