Background: Complete blood count analysis is useful for medical investigation. Multiple diseases can be diagnosed using hematological profiles. White blood cell counts, platelet counts, and red blood cell counts are linked to cardiovascular disease. It is concerning that women have a lower incidence of cardiovascular disease than men; this could be due to hormonal changes. The purpose of this study is to measure and compare various hematological levels in male and female participants.

Methodology: The serum hematological parameters of healthy males and females were investigated and compared in a cross-sectional study. Data from medical files were obtained from healthy participants aged 4–72 who had a routine medical examination in 2017–2018. Participants with a medical history, as well as those who had been using medicines or vitamin supplements, were not permitted to participate. Sysmex XP100 Tokyo, Japan was used to measure the levels of hematological parameters.

Results: In total, 240 people met the inclusion criteria. The gender difference revealed that Hb, RBC, MCV, MCH, MCHC, WBC, and platelet levels were significantly higher (p<0.001) in men as compared to women.

Conclusion:  Our findings would serve to apprise presently available data pertaining to blood parameters, gender variation was observed.