Aim: To assess the response of Vitamin D therapy in Vitamin D deficiency induced Myopathy in Children and Adolescents

Study Design: Cross sectional study

Place and duration: This study was conducted in Pakistan Institute of Medical Sciences Islamabad, Pakistan From February 2018 to March 2020

Methodology: The demographics, clinical presentation, laboratory findings, and treatment response of children and adolescents with osteomalacic myopathy were studied. Clinical, biochemical, and radiographic evidence was used to diagnose vitamin D deficiency. Vitamin D deficiency was identified as the source of myopathic symptoms after therapy with vitamin D.

Results: In the final analysis, the children ranged in age from 21 months to 18 years. Eight children (53.33%) were under the age of six, three (26.66.5%) were between the ages of seven and twelve, and fifteen (20%) were between the ages of thirteen and eighteen. Difficulty climbing stairs was reported by 100 % of participants (n=15), followed by difficulty walking, which was reported by 93.33 % of participants (n=14). In 53.33 % of the participants (n=08), abnormal gait was seen. From 4 weeks to 6 months, patients' responses to treatment was recorded.

Conclusion: To summarize, vitamin D deficiency in children can result in myopathic symptoms. Vitamin D therapy has had a fantastic clinical response. All the study participants responded to vitamin D therapy

Keywords: Children, myopathy, osteomalacia, rickets, Vitamin-D deficiency