The aim of the present study was to know the effects of home-based exercise and self-regulative techniques on flexibility and anxiety among middle-aged men. To attain the purpose of the study forty-five healthy middle-aged men accept to volunteer and their age between 45 and 50 years. They are teaching and non-teaching staff at Government Degree College, Sopore, Jammu and Kashmir UT. The subjects were randomly assigned into three equal groups, in which group - I (n=15) underwent home-based physical exercise, group - II (n=15) underwent self-regulative techniques and group – III (n=15) acted as a control. The relevant training program was given to the experimental groups for six days per week for twelve weeks. The control group did not perform any kind of structured physical activity. The criterion variables selected for the present study were: flexibility and anxiety. To measure the flexibility, the investigator used V-Sit and Reach test box and for testing the anxiety, the researcher used Hamilton Anxiety Rating (HAM-A) scale. The data was collected prior to and after experimentation from both the training groups and the control group. Paired‘t’ test was applied to examine the change within the groups and find out the significant differences between the groups the Analysis of Covariance (ANCOVA) was applied. Whenever the ‘F’ ratio of the adjusted post-test mean was found to be significant, Scheffe’s post hoc test was employed. The result of the present study indicates that there was a significant improvement in flexibility and a significant decrease in anxiety due to the effect of home-based physical exercise and self-regulative techniques when compared with a control group.  There was a significant difference found between the training groups on flexibility and anxiety, in which the home-based exercise group has better performance than the self-regulative techniques group.