Rabbit syndrome (RS) is a rhythmic movement of the mouth and lips caused by antipsychotics that resembles rabbit munching. There is no tongue involved in the movement, which is solely vertical and has a frequency of about 5 Hz. Long-term use of first-generation neuroleptics has been proven to cause RS, but nothing is known regarding the risk of RS from newer atypical antipsychotics. Aripiprazole is a new dopaminergic drug that has been demonstrated to be clinically effective as an antipsychotic with little extrapyramidal motor adverse effects. We describe the case of a 47-year-old male patient who got RS while being managed with aripiprazole for delirious mania. The current case emphasizes the importance of being cautious while administering aripiprazole to patients.

Index Terms- Aripiprazole, Rabbits syndrome, extrapyramidal side effects, Young's Mania Rating Scale, Delirious Mania