The rhizosphere, characterized by its unique soil environment influenced by root exudates and microbial communities, is fundamental to plant health and soil fertility. Among the myriad stressors affecting plant growth, cadmium (Cd) contamination stands out for its extensive toxicity and widespread prevalence, posing significant Challenges to agricultural productivity and food safety. This review article delves into the critical role of the rhizosphere microbiome in bolstering plant adaptability under conditions of high soil cadmium, offering a comprehensive comparative analysis across various plant species. It underscores the sophisticated mechanisms through which the rhizosphere microbiome mediates stress mitigation, including cadmium detoxification. modulation of plant physiological responses, and enhancement of nutrient assimilation. The synthesis of current findings reveals the significant potential of leveraging rhizosphere microbiome dynamics for the development of innovative strategies implied at enhancing plant resilience to cadmium stress. This exploration not only sheds light on the intricate interactions between plants and their rhizosphere microbiomes but also sets the stage for future research endeavors focused on harnessing these relationships for the advancement of sustainable agricultural practices. Through a detailed comparative analysis, this review illuminates the pathway forward in employing microbial-assisted phytoremediation and biofortificatio strategies to mitigate the adverse effects of cadmium contamination, thereby contributing to the resilience and sustainability of agro- ecosystems in the face of environmental stressors.

Key Words:  Cadmium, Rhizophere, microbes, plant, environment