Background: The relationship between thyroid dysfunction and breast cancer is debated. To clarify this association issue, aimed current study to Assessment level of Thyroid Peroxidase (Anti TPO) and Anti Thyrogobuilne (Anti Tg) in iraqi wemon with Breast Cancer and Autoimmune Thyroid Disease as well as study the carrelated between them.Paetint and Methods:From Oncology Teaching Hospital Baghdad , collected about 100 sera from women during the period January 2020 – June 2021 , The ages ranged from (19-70) years of Iraqi women.used CL900i for determine the level of Anti TPO and Anti TG .Results :higher percentage in patients who have thyroid autoimmune with breast cancer patients as (No.= 16; 45.7%) in age group (≥60) years, while (No.= 12; 34.2%), in age group (40-49) years (< 0.01) HS,high level AntiTPO in both Thyroid autoimmune and Breast cancer patients as (16.19±12.77) and level of AntiTg for Breast Cancer with thyroid Autoimmune as (25.31%), compared to Control lower level Anti Tg. Conclusion: There is a relationship between levels anti thyroid peroxidase (anti TPO) and Anti Tg with Thyroid autoimmune disorder and Breast cancer.

keywords: Thyroid Peroxidase (Anti TPO); Anti Thyrogobuilne (Anti Tg; Breast Cancer; Autoimmune Thyroid Disease