Withania coagulans L. Dunal, member of Solonaceae family is a valuable plant holding a key place in Ayurvedic medicines. Presence of biomedical compounds as secondary metabolites imparts anti-microbial, anti-inflammatory, anti-oxidant and anti-cancerous properties to the W. Coagualans Dunal. Various analysis was performed to evaluate the genomic aspects of the Withania coagulans Dunal.  In this study the W. coagulans Dunal genes were selected and their genomic structure, evolutionary analysis, gene structure analysis, motif enrichment analysis and secondary structure prediction was being performed to decode the genomic aspect. All genes were divided in 4 families based on their evolutionary relationship, Family 1,2,3 and 4 contain 5,3,1 and 6 genes respectively. Gene structure analysis confirmed that four genes include only CDS sequences, one contains two introns, and six contain both introns and CDS. Meme Suite predicted the existence of five motifs. Out of the five motifs anticipated, two were not predicted, while three motifs with 50, 30, and 50 amino acids were predicted, with the description Ribosomal protein uS12. With 41% Predominant structure of accD protein was Random coil. Majority of amino-acids inthe accD form extracellular portion of the protein. These findings will help the scientists to do novel work on the genomic aspects of Withania coagulans Dunal in future.  

Keywords: accD, 2D structure, in sillico analysis, proteomic analysis