The present study investigates the effects of heat generation and radiation in unsteady MHD mixed convective flow of nanofluids along a upstanding channel in the presence of porous medium. In this study we investigate Water based – Cu and TiO2 , here Water is taken as convectional base fluid , Cu and TiO2 particles are incorporated in this base fluid. Keeping in mind the congregating and random motion of nanoparticles, “Koo and Kleinstreuer model” is used. The main characteristics of the nanofluids have finer thermo physical properties such as high thermal conductivity, minimal bloking in flow passage, long term solidity and uniformity. The governing boundary layer equations are formulated and reduced to a set of ordinary differential equations using perturbation technique. Solutions are obtained for motion and temperature, discussed and pertinent results are shown through graphs. 
 
 
Key words- Radiation, Heat generation, Mixed convection, Nanofluids, Brownian motion.