The present study aimed to investigate the antioxidant, thrombolytic activity and lipid peroxidation inhibition of different extracts prepared from petals of Polianthes graminifolia (Deep Red) & Polianthes palustris (White) using several solvents. The extracts were obtained by methanol and ethanol (100% and 80%), decoction, and distilled water. The antioxidant capacity was determined by H₂O₂ scavenging assay and lipid peroxidation inhibition. Spectrophotometric analysis of clot lysis was used to determine thrombolytic activity. Ethanol and methanol extracts showed a marked scavenging activity against DPPH radical, with IC50 values being lower in potency. Their thrombolytic potential was significant, and ethanol extracts were more effective. Contents of phenolic compounds and antioxidant & thrombolytic activities were higher in the aqueous ethanol extracts. These results demonstrate that Polianthes species are potential sources of novel antioxidant and thrombolytic molecules, which could be useful in the pharmaceutical and nutraceutical industries. This would benefit from further work to identify the bioactive compounds and other specific modes of action.

Keywords: Tuberosa, Polinathes, total phenolic content, total flavonoid content, antioxidant activity