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Ultrasound assisted extraction and biological profile evaluation of Java plum extract

. Ayesha Parveen, Muhammad Suleman & Freeha Hafeez


Abstract

The present study was designed to evaluate the antioxidant activity of acetone and methanol extracts from different parts of Syzygium jambolanum in aspirin induced ulcerogenic effect. Red leaves, seed and bark of the plant were extracted by several methods (Soxhlet, ultrasound-assisted agitated bed with or without combination) for extracting bioactive compounds. The extracts also differ in TPC and TFC values based on chemical analyses. A great symbolism of its antioxidant power were the highest TPC and TFC values landed by mango peel aqueous ethanol extracts. DPPH radical scavenging assay revealed a different level of inhibition seen within each extract and intra-extracts, with the aqueous ethanol extracts demonstrated the strongest antioxidant properties compared to their other solvent counterparts based on calculated IC50 values. Significance of the results was confirmed using statistical analysis (p<0.05). These findings demonstrate important pharmacological applications of java plum which could act as a potent bio-antioxidative agent and also useful in food industry to protect against oxidative stress-related diseases.


Keywords: Syzygium jambolanum, java plum, antioxidant activity, total phenolics, total flavonoids, DPPH assay.

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