Objectives:

To compare the effects of Mobilization with Movement on pain and quality of life in knee osteoarthritis patients with Sham Mobilization.

Methodology: ARCT was conducted in DHQ Hospital and Faisal Hospital Faisalabad for four months; May-August 2023 on 54 individuals allocated into two groups by lottery method. One group received Mobilization with Movement(MWM)while the other received Sham Mobilization for 4weeks by taking measurements of NPRS, SF-12 (PCS and MCS), and knee ROMsatbaselineandtheendof theintervention. The data was collected from patients after obtaininginformedconsent. The Faisal Institute of Health Sciences signed an ethical letter for the study. An Independent sample T-test and Paired sample T-test were used for normally distributed data while the Mann-Whitney test and Wilcoxon Signed Rank test were used for abnormally distributed data.

Results: There was a significant difference in NPRS, SF-12, and knee ROMS values between the two groups.(NPRS p=0.000,PCSSF-12p<0.04,MCSSF-12p<0.04,and all ROM p<0.05).However, the MWM group was more effective in reducing pain, enhancing the QOL, and improving ROM as compared to the SM group; NPRS (3.25±0.98,4.87±1.15),PCS of SF-12(38.58±5.59,34.83±4.97), MCS of SF-12(56.29±6.18,50.79±5.99) and all ROMs (p<0.05).

Conclusion: The study showed that Mobilization with movement was moreeffectivethan sham mobilizationforpatients withkneeosteoarthritis.

Keywords: Knee Osteoarthritis, Mobilization with Movement, Quality of Life, Pain.