The main focus of this review article is the issues surrounding around the adoption of GMOs. The impacts of GMOs are complex with both pros and cons that need to be discussed. This review goes through the benefits and problems, and their numerous implications ranging from the fact that we will be able to produce more crops and use less pesticides to the fact that people are worried about the gene flow, the health risks, and the ethical considerations. The case studies bring to the real-world effects of Bt crops, herbicide-tolerant varieties, and the fortified crops. However, they stress the importance of the regulatory frameworks in the evaluation of safety and the role they play in the bringing the change. Besides of all this, the review also reveals new developments in genetic engineering, the power of sustainable practices, and the need for constant observation. The whole concern is to secure food for the whole world and to be sustainable on this Earth and the best way to do that is to have a balanced approach that concerns the scientific accuracy, the review of the ethical side, and the responsiveness of the regulatory side in order to set the path to the future of GMOs'