This paper is based on the triple Helix knowledge transfer partnership along the innovation Spectrum. The triple helix innovation framework has been widely adopted and  applied by policy makers has participated in the transformation of each Triple Helix systems provide a fine-grained view of innovation actors and the relationships between them, in a vision of a dynamic, boundary-spanning and diachronic transition of knowledge flows within the system. Triple Helix systems accommodate both institutional and individual roles in innovation and explain variations in innovative performance in relation to the development of and articulation between the knowledge, innovation and consensus spaces. Transcending sectoral or technology boundaries, Triple Helix systems emphasize boundary permeability among the institutional spheres as an important source of organizational creativity, allowing individuals to move within and between the spheres and engage in recombination of elements to create new types of organizations. Empirical guidelines for policy makers, university and business managers can be derived from this analytical framework, in order to strengthen collaboration among Triple Helix actors and enhance regional development.

Key Words: Triple, Helix, Knowledge, Transfer, Partnership, Innovation, Spectrum