Objectives: The objective of this recent study was to compare and evaluate the effects of two different muscle energy techniques in improving functional status.

Methods: A single blinded, randomized clinical design was conducted. A number of participants were screened who met the inclusion criteria of the study were selected from public and government hospitals of Faisalabad. The participants were divided randomly into two treatment groups by using the lottery method. The patients were allocated by convenient sampling into two groups. The functional status assessed by using western ontario and mcmaster universities arthritis index. Data was analyzed through SPSS 20.

Results: Both techniques were significantly effective (p<0.05) in improving      functional status. PIR was more effective compare to RI.

Conclusion: In osteoarthritis patients, post isometric relaxation muscle energy technique was found to be more effective than reciprocal inhibition muscular energy technique in improving functional activities.

Keywords: Knee Osteoarthritis, Functional disability, Muscle energy techniques