Triamcinolone is a synthetic glucocorticoid widely used. Glucocorticoids have a wide range of impacts on physiological processes. The present research was conducted to explore the deleterious effects of triamcinolone on vital organs like the liver, kidneys, muscles, and brain in common quail. Total 120 birds were purchased from the market.60 birds were used in winter and 60 in spring trial. These divided into three groups one kept as control, second group was given (low concentration 0.02ml/mg) and third group received are (high concentration 0.04ml/mg) of Triamcinolone. Clinical manifestations include such as vision impairment, formation of skin blisters, irritation, congested nasal passages, scaling of the skin, redness at the injection site and feelings of nausea. Histopathological examination of different tissues the impact of steroids on the serum biochemistry profile revealed significant harm to essential organs, with elevated levels of cholesterol and uric acid in both the liver and kidneys.The liver tissue samples showed hepatocytes arranged in chains, pyknotic and necrotic changes in a few regions, moderate cytoplasm swelling and no nuclei.Extensive vaculation of the showed kidney tissue sample and focal necrosis tubular inflammation can be observed. Although, there was no change we observed in the control group. Muscle tissue samples showed cell swelling.Likewise, in brain tissue samples, we observed blurry swelling and inflammation. However there is no change in the control group was observed.

Key Words: Triamcinolone, Quail, Histokinetics, Myofibers, Vacuolation, Glucocorticoids.