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Development, Formulation and evaluation of anti aging gel utilizing Allium Cepa Extracts

. Asifa Noureen, Iqra Afzal, Freeha Hafeez, Mateen Iqbal, Muhammad Suleman & Bisma


Abstract

Objective: This present study introduces a novel herbal formulation for an antiaging gel derived from Allium cepa (onion) skin, aiming to provide a natural and effective solution for skin reconstruction. The formulation connects the potent antioxidant and anti-inflammatory properties inherent in Allium cepa skin extracts, which have been traditionally recognized for their therapeutic benefits.

Methods: The gel is developed through a meticulous extraction process, preserving the bioactive compounds responsible for combating oxidative stress, reducing fine lines, and promoting collagen synthesis. The formulated herbal antiaging  gel contain Allium cepa skin extract, a mixture of herbal extracts (aloe vera gel extract, grape seed extract), nourishing oil (jojoba

 

 

 

 

 

 

oil, tender coconut oil) gelling agent (carbopol 934) and pharmaceutical chemicals (methylparabene, propyl parabene, propylene glycol ,Vitamin E).

Results: The herbal antiaging gel (F5) which contain  different fractions 0.1 g to 2.5g of Allium cepa skin and all herbal extract and gelling agent showed maximum antiaging effect. Preformulation studies was on physical parameters like

color, odor, consistency, greasiness, homogeneity and water washability. Pharmaceutical parameters such as pH, spreadability, viscosity and drug content were also evaluated. Antioxidant activities showed that F5 high DPPH scavenging ability 61.54 in ascorbic acid the best formulation was (F5).

Conclusions: Furthermore, the formulation undergoes rigorous safety and stability assessments, ensuring its suitability for topical application. Results from dermatological evaluations, including skin hydration, texture, and wrinkle reduction, provide valuable insights into the efficacy of the antiaging gel. So, its concluded that Allium cepa skin can have a good  formulation for antiaging gel.

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