The majority of patients with Acute Myocardial Infarction (AMI) are treated at centers with primary Percutaneous coronary intervention (PCI) facilities open all the time, however, the level of care varies on weekdays (regular hours) and on days off, holidays, and nighttime (off-hours). Comparing the therapeutic outcomes of individuals receiving primary coronary intervention (PCI) for acute myocardial infarction with ST elevation (STEMI) at a higher-level cardiac center at non-regular and regular work hours was the major goal of the study. A total of 666 participants were recruited and split evenly into groups according to regular time (unexposed) and non-regular time (exposed). Time from door to balloon was noted. In order to track the mortality rate in hospitals, individuals were monitored during the time they were hospitalized. A door-to-balloon time analysis was made between the exposed and unexposed groups. It was determined whether exposure as well as mortality in hospitals were related. A P-value of less than 0.05 was considered statistically significant. According to the statistics, the research included a total of 19.06 % female patients (Group B) and 73.3 percent male patients (Group A). In contrast, there were 26.7 percent female participants and 80.9 percent male patients in Group B.  In group B, 68.5 percent of patients had high blood pressure, 64.6 percent had diabetes mellitus, 5.5 percent were smoking, 0% had CAD family history, and zero percent had obesity. In group A, 48.6 percent of patients had high blood pressure, 45.3 percent had diabetes mellitus, 22.3 % were smoking, and 4.5 percent had a CAD family history. Of the patients in group A, 24.9 percent had SVD, 34 percent had 2VD, and 41.2 percent had 3VD. In contrast, group B included 42.5 percent of patients with SVD, 3.6 percent with 2VD, and 18.9 percent with 3VD. The most prevalent disease location in both groups A (62.3 percent) and B (44.1 percent) was the left anterior descending Also, the study discovered no connection between study groups and in-hospital mortality that was noteworthy. Patients with STEMI receiving primary PCI who presented outside of normal working hours did not significantly affect the death rate in the hospital or door-to-balloon time

Keywords: Total Hours of Duty, Acute STEMI, Primary Percutaneous Coronary Intervention (PCI), and Outcomes