Schiff bases are the condensation products of primary amines with aldehydes or ketones in which the carbonyl group is replaced by imine or azomethine. They are valuable class of organic compounds and able to coordinate a number of different metal ions, hence stabilizing them in a variety of oxidation states. The chemistry of transition metal complexes with Schiff bases is quite rich in terms of applicability. The importance of polydentate Schiff bases cannot be ignored because they can easily be attached to a metal ion due to the formation of highly stable chelates, which are necessary for their action under certain tough conditions. The chemistry of Schiff's bases has attracted chemists for having active role in biological field and a wide range of biological applications such as antiviral, anticancer, anti-bacterial, antifungal, antioxidant, analgesic and antiglycation properties. Moreover, a variety of Schiff bases can inhibit the enzymatic actions due to their structural compatibility to biological systems. The compound containing thiazole moiety show excellent biological activities. Thiazide derivatives of natural or synthetic origin have been applied as antibacterial, antifungal, anticancer and antiviral agents. Keeping in view the above mentioned applications, in the current study Schiff bases 1 and its complex 2 was synthesize and structurally characterize by commonly used spectroscopic technique (NMR). The antibacterial activity of the synthesized compounds has been determined.

Index Terms- Cobalt Schiff base complexes, Synthesis, Characterization, Thiazole ligands, Metal-organic complexes