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Toxic effect of induced arsenic doses on the complete blood count and serum biochemistry in Quails

. Saima Noreen, Dr. Mubashir Aziz, Sidra Muhyuddin, Humaira Asim & Rimsha Waheed


Abstract

Arsenic is a natural metalloid which is present in the universe everywhere. Poisoning of arsenic is major issue that affects different species. Current study was performed to investigate the toxic effects of feeding inorganic heavy metals such as arsenic on complete blood count and blood chemistry of common quail. Total 120 birds were purchased from the market.60 birds were used in winter and 60 in spring trial. These divided into three groups one kept as control, second group was given (low concentration @ 1.5mg) and third group received are (high concentration @ 2.5mg) of arsenic. Clinical signs including diarrhea and appetite loss were exhibited in all treated birds. A decrease in body weight was observed in all treated groups, while control group birds gain weight. Impact of arsenic on blood parameters was that number of red blood cells, level of hemoglobin and MCH decreased. Number of white blood cells, value of MCV, alanine amino transferase, aspartate amino transferase   and cholesterol increased. Analysis of data revealed that the reduction in number of red blood cells and level of hemoglobin were significant (p<0.05), while number of white blood cells increased. MCV, the significant value of Cholesterol was also observed in birds affected by high dose of arsenic as compared to control and low dose treated bird. In creatinine and globulins significantly changed was also observed.

Key Words:  Mean corpuscular hemoglobin (MCH), Mean cell volume (MCV).

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