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Formulation, In-Vitro Characterization, Antioxidant Potential and vicissitude in rheological parameter of Cosmeceutical Cream Containing Brassica oleracea Extract.

. Qazi Adnan, Sehrish Rafiq, Naveed Akhtar, Muhammad Younus, Haji Muhammad Shoaib Khan, Jafir Hussian Shirazi. Shahid Muhammad Iqbal, Hamna Sabir, Nimrah Mehmood, Umer Shaukat, Marwah Rehman, Muhammad Yousuf, Muhammad Saleem Qureshi, Muhammad Naeem, Mu


Abstract

Study’s aim was to incorporate 3% ethanolic extract of Brassica oleracea into oil in water emulsion to get a stable cream and to find out antioxidant, tyrosinase inhibition potential along with characterization of stable cream formulation.  Brassica oleracea ethanolic extract had 74.2% antioxidant activity, determined by using the DPPH method. TPCs were 115.75 mgGAE/g and the TFCs were 5.62 mg QE/g. Cream incorporated liquid Paraffin, Tago® care 450, Cetostearyl alcohol, stearic acid and ethanolic extract of Brassica oleracea. Samples of control and formulation were stored at various storage temperatures for 28-days to assess the stability of newly formulated cream. These were evaluated for different organoleptic changes, pH and rheology studies. Both samples of active and test samples did not show phase separation and exhibit agreeable range of pH and rheology. So, both formulations found stable along with antioxidant potential of ethanolic extract of Brassica oleracea also presented its antiaging use and applications in the various fields of medicine and cosmetics industries.
 

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