The aim of this study was to evaluate changes in skin erythema, skin melanin, skin hydration, skin elasticity, skin sebum and skin number of pores during three months application of cosmetic emulgel loaded with Piper nigrum seed extract. Base without plant extract and 4% plant extract loaded emulgel was prepared. The base and plant extract loaded formulation were applied on cheeks of healthy volunteers (n=13). Hydration level of skin was statistically significantly (p˂0.05) increased by plant extract loaded formulation. The formulation demonstrated a statistically significant (p˂0.05) decrease in skin melanin content while the base had insignificant (p > 0.05) effects. The formulation greatly decreased skin erythema level (p˂0.05). Regarding sensory evaluation, both emulgel were aesthetics. The topical, non-invasive application of Piper nigrum seeds extract loaded emulgel shown a remarkable decrease in number of pores on human skin. This study will bolster interest in research and conviction in the use of natural remedies.