Background: Data on the use of medicinal plants in the treatment of various diseases by indigenous community was collected for Two-year period.

Objective: The objective of current study to record, document, and preserve the indigenous ability of plants and develop natural remedies for medicinal plant species. Also to evaluate different aspects and medicinal plant preferences among the four distinct valleys (Chinglai, Chamla, Gokand, and Chagharzai) of Buner, Khyber Pakhtunkhwa, Pakistan.

Method: We figured out the use value (UV) and conservation status (CS) of every single plant species. In the present study,

Result: we found a total of 142 species from 65 families that could potentially be utilized to treat a variety of ailments. Our study indicates that leaves are the most common plant part used by an indigenous community. The UV varied from 0.05 Sorghum halepense reported in Gokand. To 0.91 Azadirachta indica. Reported in Chagharzai. The medicinal plant conservation status indicated that 38 plant species were Infrequent, followed by 37 Rare, similarly, 35 species and 6 species respectively declared as Vulnerable and Endangered due to their respective utilization.

Conclusions: The study found that the traditional knowledge of medicinal plants is largely held by elderly people and is mainly transmitted orally from generation to generation. Each valley had its own unique set of medicinal plants, which reflects the diversity of the local flora and the cultural diversity of the communities living in these valleys. Traditional plant applications necessitate conservation techniques and more research in order to make more efficient use of environmental assets.

Keywords:  Comparative study; indigenous; ethnobotanical; diversity of medicinal plant; Buner; Pakistan