Covid-19 is an infectious disease caused by the SARS-CoV-2. This virus has undergone mutations which has resulted in evolution of its several variants so far. The technical advisory group of World Health Organization (WHO) have declared all such SARS-CoV-2 variants (alpha, beta, gamma delta, & lambda) as variants of concern (VOC). These variants were quite challenging in terms of being fatal, hence, many therapeutic strategies were devised to restrict their infectibility. In this regard, multiple approaches were formulated by the scientists to possibly limit the spread of SARS-CoV-2. Our main concern in this study is also to analyze and summarize information regarding such strategies to treat COVID-19 infection. The mainly focused areas regarding this aspect in this study include traditional therapeutic practices, comprising vaccination and oral antiviral drugs. Moreover, some of the advanced breakthroughs in this area have also been discussed which include anti-inflammatory agents, corticosteroids and nanobody-like molecules.

Keywords: Antiviral drugs, COVID-19 infection, Immunotherapy, SARS-CoV-2, SARS-CoV-2 variants, Therapeutics, Vaccines.