This cross-sectional study was carried out in collaboration with the University of Karachi's department of biochemistry and the dialysis unit of the nephrology wards of the JPMC and PNS Shifa Hospital, Karachi. The investigation was conducted between April 20, 2020, and October 5, 2022. The study received ethical approval from both the PNS Shifa Hospital Karachi ethics committee and the JPMC Karachi institutional review committee. A total of 83 hemodialysis patients and 83 controls were recruited in the study after applying inclusion and exclusion criteria.

Results

The results of our study showed a significant increase in LDL Cholesterol, Total Cholesterol and triglycerides in hemodialysis patients while a significant decrease was seen in HDL levels as compared to normal control group.

Conclusion

Hemodialysis patients exhibit distinct dyslipidemia patterns, potentially elevating their cardiovascular risk. The study's findings highlight the urgent need for tailored interventions to manage these lipid abnormalities. Future research should focus on understanding the underlying mechanisms and devising effective therapeutic strategies.

KEYWORDS:

Dyslipidemia, Hemodialysis , Lipid Profile.