Dental implants inserted into the jawbone, where they fuse to provide a stable, durable foundation for restorations. However, even the best dental implants can fail. Therefore, researchers focus on developing surface coatings for implants to enhance Osseointegration. Objectives of this study are to form a biodegradable scaffold by electrospinning of ascorbic acid, collagen, and polycaprolactone (PCL) fibers onto the surface of commercial pure titanium (CpTi)  implants.

Methods three composite fibers (scaffold) created using the electrospinning procedure first scaffold formed from collagen/PCL, the second scaffold formed from ascorbic acid added to the collagen/PCL, and finally the third scaffold formed from PCL polymer alone with ascorbic acid. After that characterization done by SEM, AFM , scaffolds cross cut test, and wettability. Another part of study include examination of histological response for coated and uncoated implant in femur of rabbits statistical analysis of data was performed by SPSS version 22. The results of SEM analysis revealed the formation of nanofiber scaffold with pores. while the results of AFM surface roughness indicate that the  ascorbic acid/PCL scaffold had the roughest surface compared to the other two groups .And the collagen /PCL scaffold appears to have a rather smooth topography,. Histological finding after 2 and 6 week of implantation appear show thicker layer of fibrous osteogenic cells  in ascorbic acid loaded to collagen/PCL  coat on  CpTi . The cross-cut test demonstrates that scaffold adhesion to CpTi is robust and strong. within limitation of this study it can be concluded that Ascorbic acid with collagen can be efficiently coat titanium surface by using electrospinning technique. In addition, a scaffold formed with an appropriate properties include improve hydrophicity of surface and increase surface roughness in addition to increase shear bond between implant and bone.

Key word:

Electrospinning scaffold, ascorbic acid, biochemical coating, implant coating, collagen scaffold