Background: Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in women of reproductive age, and urinary tract infections (UTIs) in women are one of the most common infections occurring at various stages of life. , therefore the aim of the current study is to investigate the relationship between polycystic ovary syndrome (PCOS) and urinary tract infections (UTIs) in Iraqi women. Patients and methods: about 150 blood and urine samples were collected from PCOS women during the period (April to September ) 2022 from Ramadi Teaching Hospital, As well as a group of healthy women  (50samples) as a control. PCOS diagnosis based on clinical and biochemical criteria also using an ultrasound device (Ovarian ultrasound showing 8 or more subcapsular cysts that are less than 10 mm in diameter together with thickened ovarian stroma.). As for the investigation of UTIs performed it was as follows: GUE for mid-stream urine and cultured on both agar (MacConkey's and blood media), Gram staining, and other routine tests were used to identify bacteria after it was cultured, as well as used Vitek 2 system.  the concentrations of T, FSH, Anti-FSH, LH, Anti- LH and E were measured with ELISA. Results: Current study revealed that more PCOS women with UTIs had irregular menstrual cycles (No. =  59, 90.77%) than regular women (No. = 6, 9.23%), married PCOS women (No. = 47, 72.30%) than single women (No. = 18, 27.70%), and gram-negative bacteria (No. =  46, 70.76%) caused UTIs more frequently than gram-positive (No. =  19, 29.24 Since Staphylococcus aureus and E. coli were the two most prevalent isolates for PCOS in the UTI group (No.=16; 24.62%), so higher concentrations of FSH, Anti-FSH, LH, and testosterone were found among PCOS women with UTIs as compared to the control group ( 5.301± 0.581;  0.514± 0.279; 5.1256±3.905; and 1.09 ± 0.10 ) respectively compared to the control group ( significant (p<0.05)), however, there was no statistically significant difference between the groups for Estradio (E2) and Anti LH ( 140.699± 33.011; 0.385±0.222) respectively compared to the control. Conclusion: The current study concluded correlated between PCOS with UTIs as well as most PCOS women with UTIs were irregular menstruation compared to regular menstruation, also married women more than single women, UTIs caused by gram-negative bacteria more than gram-positive, and both E. coli and Staphylococcus aureus were the most common bacterial isolate from  PCOS women with UTI, also higher concentrations of FSH, Anti- FSH, LH, and T hormones among PCOS women with UTIs ( significant (p<0.05), whilst no significant difference for both E2  and Anti-LH.

Keywords: Urinary Tract Infections (UTIs); polycystic ovarian syndrome (PCOS); Stein-Leventhal syndrome;; FSH; Anti- FSH; LH; T ; E2  and Anti-LH.