Preeclampsia is a hypertension condition that causes liver and kidney damage during pregnancy. Salahadeen General Hospital/Gynecology and Obstetrics department performed a case-control research from November 1, 2022, to May 30, 2023, to determine platelet and platelet indices in pregnant women with preeclampsia in the second and third trimesters. The research comprised 120 singleton pregnant women with live fetuses at 20 weeks or older. 60 pregnant women were preeclamptic, whereas the other 60 were healthy and normotensive (control group). Systolic and diastolic blood pressure values determined preeclampsia severity. Platelet count, mean platelet volume, distribution breadth, and ratio were measured in blood samples. The preeclampsia and control groups had similar age, gestational age, parity, and BMI. . However, there were significant differences in systolic and diastolic blood pressure between the two groups. The study showed that the lowest mean of platelet count (149.30±35.52 platelet×103/L) as compared with the control group (263.67±41.12 platelet×103/L). Platelet distribution width (PDW) was also reduced in Pre-eclampsia (17.13±5.37 fl) and the highest mean was in the control group (17.67±6.09 fl). The study also showed that Mean platelet value  was elevated in women with Pre-eclampsia while  Platelet count to Mean platelet volume ratio was  reduced in Pre-eclampsia. The study showed the mean of Platelet count and  Platelet distribution width were reduced in the severe cases of  preeclamptic  pregnant women  as compared with mild  preeclamptic women  while the highest mean of MPV was in severe preeclamptic women. The study showed the mean of Platelet count, Platelet distribution width (PDW) and Platelet/MPV ratio were decreased  significantly in preeclamptic  pregnant women in 3rd trimester of pregnancy as compared with women in the 2nd trimester.  While Mean platelet value  was elevated preeclamptic  pregnant women in 3rd trimester of pregnancy as compared with women in the 2nd trimester. It was concluded that women with pre-eclampsia had a significantly lower mean platelet count, platelet distribution width and Platelet count to Mean platelet volume especially in severe cases and 3rd trimester of pregnancy while mean platelet value in women was elevated.

Keywords: Platelet; Platelet Indices; Pregnant Women;  Preeclampsia