Extensive investigations into the curative attributes of various plant species are prompting a reassessment of traditional medical approaches on a global scale. The vast range of plant diversity offers exciting prospects as an untapped reservoir of novel chemicals that could be employed for medicinal purposes. Herbal medicines are particularly advantageous due to their perceived effectiveness and cost-effectiveness.

The fruit commonly known as BlackBerry is scientifically referred to as Syzygium cumini (L.) Skeels or Eugenia jambolana Lam., belong to the species of Black Plum. Historically, people have utilized the bark, stem, and leaves of this plant due to their diverse properties. The fruits and seeds of the Black Plum are utilized for managing diverse conditions such as pharyngitis, diabetes etc

The study, therefore, presents preliminary results on the analgesic and anti-inflammatory effects of S. cumini leaves, aiming to validate traditional and folkloric beliefs.

This study aimed to evaluate the assessment of ethanol extract from cumin leaves to prevent edema in Wistar rats. Oral doses during the study were 200 and 400 mg/kg. Two doses of the extract were found to inhibit the effects, confirming the use of the plant in traditional 

Medicine. Our research focused specifically on investigating the anti-inflammatory properties of cumin leaves.

Additionally, the analgesic effects of S. cumini leaves were studied using the acid-induced writhing method in mice. The ethanolic extract obtained from S. cumini leaves was compared to a 300 mg dose of acetylsalicylic acid (Aspirin). The study explored two different doses of the ethanolic extract, 300 mg/kg and 500 mg/kg. The results indicated that S. cumini leaves have significant analgesic effects. Both the 300 mg/kg and 500 mg/kg doses demonstrated considerable pain-relieving activity, comparable to the reference medication, aspirin.

Keywords: Anti-inflammatory; S.Cumini; Traditional medicine