The noval series of the chelates with the transition metals such as Zinc (II), Manganese (II), Nickel (II), Cobalt (II) and Copper (II) have been synthesize in ethanol media at 70 °C temperature from the synthesized Schiff base ligands that have been derived from 4-aminoantipyrine, ortho-phenylenediamine and different aldehydes. The synthesized ligands and their metal complexes were purified by TLC technique, and characterized by different analytical techniques i.e FTIR, NMR, Mass spectra and  checked for antioxidant and antidiabetic activities and showed excellent results.

Keywords: ortho-phenylenediamine, 4-aminoantipyrine, Schiff base, metal complexes, 5-Arylfuran-2-carbaldehydes