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Spectrophotometric method validation studies of Aspirin
The validation technique was significant in retaining the quality of the final output. We can understand the terms specificity, sensitivity, accuracy, and specific detection and quantification limits. Principle component of validation is the component of quality assurance and control. Aspirin is a salicylic drug that also functions as an anti-pyretic and an anti-inflammatory. Aspirin was used against platelet assemblage and prevent arterial and venous thrombosis. There are other analysis methods, but we prefer UV-VIS spectroscopy. The procedure of forming tablets has gone through countless studies. A rapid, sensitive, and precise UV-Vis technique was developed and validated for the quick evaluation of Aspirin. The detection, linearity, accuracy, precision, and quantification limits of the approach were all verified. The optimum circumstance for testing the medication was acknowledged. The longest desirable wavelength (max) of aspirin was detected to be 226 nm. Aspirin linear equations were detected to be y = 0.004x-0.9969 r2. Validation was performed on basis of ICH requirements for specific accuracy, linearity, precision, LOQ, and LOD. According to the performance characteristics, the proposed technique was detected to be accurate, precise, and rapid for deciding Aspirin for routine survey
Index Terms- Aspirin, UV-VIS spectroscopy, and process validation are all keyword.