In Pakistan, dengue fever has undergone significant demographic change over the past two decades, and as a result of globalization and climate change, the disease now poses a greater threat to humanity. By comparing the hematological and biochemical parameters in dengue-positive patients, this study seeks to better understand the ongoing endemic dengue fever in Peshawar, Pakistan. The cross-sectional observational study was conducted from November 2022 to January 2023 at Lady Reading Hospital in Peshawar, Khyber Pakhtunkhwa, Pakistan. A sample of 100 patients who tested positive for dengue was gathered and evaluated. Our findings show that those between 25 to 40 years are more likely to get dengue fever. The elevated alanine transaminase levels and significant p-value in the study indicated a link between dengue infection and liver cell damage. The study also discovered an increase in white blood cell count with marginally lower normal hemoglobin levels, which raises the possibility of an underlying immune system reaction or imbalance. Hematological and biochemical parameter means, however, fell within the normal range.

Keywords: Biochemical parameter, Dengue fever, hematological parameter Mosquito-borne disease