Background: Students in nursing are expected to maintain a healthy lifestyle and have a high quality of life due to their responsibility to care for patients and resolve many of their issues. The study was conducted with the aim to evaluate the well-being and academic performance of undergraduate students and their relationship with each other.

Method and Materials: An analytical cross sectional study was conducted in the ten nursing colleges of Khyber pukhtankhwa selecting as strata through stratified sampling, having 379 students from December 2022 to February 2023. Data was collected through student well-being questionnaire of well-being and students’ performance through GPA. Descriptive statistic of categorical variable was analyze through frequency and percentage, while continuous variable through mean and standard deviation. Chi-square test was applied to identify relationship between well-being and academic performance through SPSS 23.0.

Results: The total number of participants of the study was 387, where male participants were in majority (73%) compare to female participants (27%). The academic performance of the majority of the students was best (48.5%), followed by average performers (42.7%), and poor (8.7%). In best category, the students of the 4th semester performed well (14.5%) compared to other semester students. The overall well-being of the students was best. In the well-being category the positive academic self-concept has the maximum mean score (3.71 ± 0.84), followed by the positive attitude towards the school (3.70 ± 0.95), and enjoyment in the school (3.67 ± 0.80). The study reveals that well-being is significant relationship (0.000) with academic performance.

Conclusion: That study concluded that for achieving the best academic performance the student’s well-being is required to be good, but factors like high expectation of parents and school or fear of students in failing to achieve good grades affect their well-being.

KEYWORDS: well-being, academic performance, nursing students, clinical practice, nursing