Objective:

To assess the association of MDA levels with Stress, Anxiety and depression in university students from Karachi, Pakistan.

Methodology:

This is a comparative, cross-sectional study conducted in national university of science and arts, Karachi. The sample size was 69, modified Satoh method was used to quantify the amounts of MDA, while for psychological assessment, DASS (Depression, Anxiety, and Stress Scale) was used. Statistical package of social sciences (SPSS) version 21 was used to analyze the data.

Results:

Mean age was 18.4 ± 4.8 years, over all MDA mean value was determined as 3.05 ± 0.3. DASS scores were reported as higher in first year students while 16-19 years of age as compared to other groups indicating higher level of psychological issues in newly admitted students.

Conclusion:

According to the foregoing findings, the MDA levels of second-year students are higher than those of first-year & third-year students, indicating a higher level of oxidative stress in second-year students. As a result, additional work on health enhancement can be done in this population.

Keywords:

MDA, Oxidative stress, DASS