In the present study, presence of DIPEA, a combination of 2, 3-dihydro-1H-inden-2-amine and 4-chloro-2-methyl-7H-pyrrolo [2, 3-d] pyrimidine was transformed into Pyrrolo [2, 3-d] pyrimidine. The safety and convenience was carried out continuously at high temperatures is one of the key benefits of current research. The synthesis has produced good yields and they were identified using spectrum analysis.

Keywords: Synthesis, Heterocyclic compounds, Pyrimidine, Isatin derivatives and Medicinal chemistry.