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Preparation of Selected Metal Ion bound Albumin Nanoparticles

. Muhammad Arshad & Uzma Faiz


Abstract

Metal deficiency like Zinc and iron among pregnant women is a significant Global health concern especially in developing countries. About 17% of world population is affected by Zinc deficiency. Several nano systems have been studied in previous work to increase the bioavailability of micronutrients like zinc. This study is aimed to develop suitable nanoparticles that can be used in vitamin formulations as a carrier for zinc ion so that it can be highly bioavailable even using small amount of zinc. For this, BSA nanoparticles were produced in the size range of 100-200nm, and then zinc was bound with these prepared nanoparticles. After binding with zinc, the size of nanoparticles was about 600-800nm.By using characterization techniques, the results obtained showed that zinc binds with BSA nanoparticles effectively and by using this zinc bound Albumin nanoparticles in vitamin formulations, bioavailability of zinc can be enhanced in future studies.

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