Background: A pronounced increase in prevalence, coupled with vascular complications, has made diabetes mellitus type II a worldwide health problem. Diabetes established patients are commonly monitored through the measurement of glycated hemoglobin (HbA1c).

Objective: The study objective was to determine whether lipid profile in serum correlated with the level of HbA1c in patients with type II diabetes mellitus.

Methods: There were 80 diabetic participants in the present cross-sectional observational study, 40 of them men and 40 of them women, ranging in age from 27 to 75 years.

The HbA1c value was used to classify patients into 2 groups: those with a HbA1c ≤ 7% (good glycemic control) and those with a HbA1c >7% (poor glycemic control). An analysis of glucose, HbA1c, and lipid profile concentrations was conducted.

Results: A group of participants with good glycemic control had significantly lowed glucose concentrations, TAG levels, and the ratio of TAG to HDLc. A significant difference between patient groups with good and poor glycemic control was noted in the Castelli 1 and Castelli 2 indexes, in comparison with low glycemic control (p = 0.004).

Conclusion: The HbA1c-TAG ratio and HbA1c-TAG/HDL-cholesterol ratio was statistically significantly positively correlated in our study.

Keywords: Type II diabetes mellitus, lipid profile, glycemic control, HbA1c, LDL, HDL.