It is experimentally established that against the background of anaphylactic shock, significant shifts occur in the spectrum of pancreatic enzymes (alpha-amylase, protease complex and lipase), which can affect the splitting and assimilation of the main components of food. Antihistamines (dimedrol, diazoline, suprastin, fenkarol, zaditen), introduced in the process of causing anaphylactic shock, significantly correct the observed changes in the activity of the studied enzymes. And at the same time, the effectiveness of the corrective action of fenkarol and, especially, zaditen, are superior to other remedies.

Key words: antihistamines, dimedrol, diazolin, suprastin, fenkarol, zaditen, anaphylactic shock, digestive enzymes, pancreas.