In order to study the immuno-hematological risk of chronic kidney disease (CKD) progression in children with lymphatic diathesis (LD), 120 children aged from 7 to 11 years old suffering from CKD (nephrotic form of chronic glomerulonephritis (CGN) were examined. Of them: 35-CKD without LD-1-group; 35-CKD with LD-2 group; 25- LD- 3-group. It was determined that LD is a risk factor that affects the progression of CKD (nephrotic form of CGN) in children, which is confirmed by more pronounced (1.5-2 times more often) manifestations of clinical, laboratory and immunological changes in children with CKD with LD compared with children with CKD without LD. In CKD with LD, the progression of immunopathological changes and aggravation of hematological changes occur closely interconnected, manifesting a high informative combination of various immunological and hematological parameters, such as: ABL of kidneys, ABL of lungs, IgA, CIC, IL-2, CD8, NAF, hemoglobin, lymphocytosis, hypoalbuminemia, hypercholesterolemia. Highly informative combinations of various immunological and hematological parameters affecting the progression of the pathological process in CKD with LD are the criteria for an early immuno-hematological diagnosis and make it possible that LD is a predictor of the progression of renal anemia and chronic kidney deficiency in such patients.

Key words: lymphatic diathesis, chronic kidney disease, immunity, combination, progression