The current research work is designed to determined phytochemicals and anti-microbial activities from selected seven plants based chemical agents namely Plantago major, Lilium polyphyllum, Rumex dentatus, Salvia moorcroftiana, Sophora mollis, Marrubium vulgare, Olea ferruginea. Different four chemicals (n-hexane, ethyl acetate, methanol, extract and distilled water) are used for extraction. The different extracts like n-Hexane, ethyl acetate, methanol, and distal water percentage extractive values of the seven selected medicinal plant were studied. The highest n-Hexane extractive values was recorded for Olea ferruginea 151% the next one was salvia moorcroftiana (Stem, flower) 128% then followed by Lilium polyphyllum and least for Rumex dentatus, Plantago major and salvia moorcroftiana (roots). The presence of alkaloids was recorded for Lilium polyphyllum, Rumex dentatus, Salvia moorcroftiana, Sophora mollis, Olea ferruginea While glycosides were present in Salvia moorcroftiana and Sophora mollis. Similarly Steroids and triterpenoid were present in Lilium polyphyllum, Salvia moorcroftiana (in stem, root) and Rumex dentatus. The tannins were absent in Olea ferruginea and Salvia moorcroftiana root while flavonoids were absent in Rumex dentatus, Plantago major and Olea ferruginea. Plantago major, Rumex dentatus, Sophora mollis, and Marrubium vulgare showed positive results for Phenols and Plantago major, Rumex dentatus, Salvia moorcroftiana showed the presence of protein.

The plants extract are also tested for their antimicrobial activities against tested microbes, through well diffusion method. The results showed that three therapeutic plants (Rumex dentatus, Salvia moorcroftiana, Plantago major, Lilium polyphyllum (Distilled water extract) and Marrubium vulgare) demonstrated significant activities against tested microbes. While the remaining two plants (Olea ferruginea and Sophora mollis) no activities against tested microbes.

Index Terms- Phytochemical, anti-microbial, medicinal plants, Plant extracts, Kurram