Background: Type-II diabetes mellitus (T2DM) is a chronic disease characterised by persistent hyperglycemia and is associated with many complications and high morbidity. Smoking is a risk factor that can precipitate many complications of diabetes, including increases in HbA1c levels in patients with T2DM.

Materials and Methods: The study population included 100 type II diabetic male patients with a history of moderate smoking and 100 type II diabetic male patients with no smoking history. HbA1c levels were estimated using Microlab 300 at wavelength 415 nm against water as a blank (Fast Ion-Exchange Resin Separation Method).

Results and Conclusion: There was a significant increase after a period of 4 months in blood HbA1c levels (p.000) in type 2 diabetics with a history of smoking. On the contrary, there was no significant increase (p >.05) in HbA1c levels in type 2 diabetes mellitus nonsmokers. A significant increase was observed in HBA1c in smokers as compared to non-smokers. They were concluding that smoking affects the HbA1c level but no other factors.

Key Words: Type-II diabetes mellitus, HbA1c, smokers, Non-smokers.