Objective

To determine the prevalence of OPMDS and to assess the association between their clinical and histopathological features.

Methodology:

This cross sectional study was conducted on patients with OPMDs visiting abbasi Shaheed hospital and ziauddin university hospital. OPMD lesions include OSF, leukoplakia, erythroplakia, lichenplanus and actinic keratosis. All lesions were examined and diagnosed clinically as well as histopathologically. Written informed consent was obtained and all data was analyzed on SPSS version 20.0.

Result

Oral potentially malignant lesions were significantly associated with gender (p-value 0.002) and habit (p-value0.007). Among all lesions, the buccal mucosa was the most prevalent site but no significant association was observed with sites. However smoking was significantly higher among all patients(p-value 0.007) .Moreover the comparison of clinical and histopathological diagnosis showed the importance of histopathological confirmation of OPMD lesions.

Conclusion

Diagnosing oral lesions in early stage may aid in preventing the transformation of these OPMDs into malignancy.As most of the lesions remain undiagnosed due to their asymptomatic nature and similar appearances. Therefore histopathological confirmation is necessary with clinical examination.

Key words

Oral potentially malignant disorder, clinical diagnosis, histopathology