Ozone application in care of oral health arises as innovative and unconventional treatment modality in dental practices. Ozone is a kind of oxygen that has a positive impact in oral diseases managed by numerous ways of treatment options. Its distinctive features are analgesic, immunostimulant, antimicrobial, antihypnotic, detoxicating, bio-energetic and biosynthetic functions. Its pain free, atraumatic, non-invasive nature, and comparative lack of discomfort and fewer side effects raise the patient’s competency and acceptability ensuring it as a perfect treatment option. This review generally highlights the efficacy of ozone in oral health care management and its remedial prospective along with its clinical use in periodontology, endodontic, restorative dentistry, oral pathologies, oral surgery, prosthodontics, orthodontics, wound healing, and tooth mineralization.

Keywords: Antimicrobial, Caries Lesion, Ozone therapy, ,Root Caries ,Hypersensitive teeth