Objective: To assess the effect of topical administration of 5% EMLA and 20% Benzocaine on the discomfort associated with local anaesthetic agent injection in an adult population.

Methods: The participants will be briefed on the nature and goal of the study including visual analogue scale (VAS). The areas will be separated into condition A- 5 percent EMLA and Condition B – 20 percent Benzocaine Gel. After marking injection sites, primary investigator will leave the room and the consultant will apply 5 percent EMLA gel at experimental area and 20 percent Benzocaine gel at control area. After pre-treatment with topical anaesthetic the consultant will deliver local anaesthesia to both sides. Then Principal investigator will be notified into the room and patient will be examined though visual analogue scale by him/her.

Results: Participants in the study were between the ages of 18 and 35, with a median age of 29.4 years. At three minutes, benzocaine group received a VAS score of 4.00; at six minutes, it received a VAS score of 4.23; at nine minutes, the EMLA group received a VAS score of 3.00 with a standard deviation of 2.04; and at nine minutes, it received a VAS score of 3.00. At three, six, and nine minutes, the Benzocaine group have higher VAS means than EMLA group (p-value 0.05). Between the Benzocaine and EMLA groups, there was no statistically significant difference. Both benzocaine and EMLA had comparable efficacy in both sexes. In neither group, individuals' ages had no effect on their VAS scores.

Conclusion:The authors propose applying topical analgesics on a regular basis. There are no known hazards linked with topical anaesthetics while accocrding to the recent study, 5% EMLA found to be superior to 20% Benzocaine group.